Author

J. G. Knudsen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

J. A. Kellard· 2 shared L. Briant· 2 shared P. Rorsman· 2 shared A. Benrick· 1 shared A. Kim· 1 shared A. Spigelman· 1 shared B. B. Lowell· 1 shared C. Miranda· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCell Biology

J. A. Kellard

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2 papers

Recent·Most cited

Reduced somatostatin signalling leads to hypersecretion of glucagon in mice fed a high fat diet

J. A. Kellard, N. J. G. Rorsman, T. G. Hill, S. L. Armour, M. van der Bunt, P. Rorsman, J. G. Knudsen, L. Briant

This study shows that reduced somatostatin signaling in mice on a high fat diet leads to increased glucagon secretion, contributing to hyperglucagonaemia.

bioRxiv · Apr 7, 2020Cell Biology

Arginine-vasopressin mediates counter-regulatory glucagon release and is diminished in type 1 diabetes

A. Kim, J. G. Knudsen, J. C. Madara, A. Benrick, T. Hill, L. Abdul Kadir, J. A. Kellard, L. Mellander, C. Miranda, H. Lin, T. James, K. Suba, A. Spigelman, Y. Wu, P. MacDonald, , L. Briant

This study identifies arginine-vasopressin as a systemic regulator of glucagon secretion, showing its role in counter-regulatory responses to hypoglycemia and its impairment in type 1 diabetes.

bioRxiv · Jan 30, 2020Cell Biology