Author

N. J. G. Rorsman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:protein structure prediction· 1 Assay:structural biology· 1

Frequent Co-Authors

A. Accardi· 1 shared A. C. W. Pike· 1 shared A. Chu· 1 shared A. Tessitore· 1 shared C. A. Shintre· 1 shared C. M. Ta· 1 shared E. P. Carpenter· 1 shared J. A. Kellard· 1 shared

Activity by Year

2018-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperBiochemistry

A. Accardi

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2 papers

Recent·Most cited

Reduced somatostatin signalling leads to hypersecretion of glucagon in mice fed a high fat diet

J. A. Kellard, N. J. G. Rorsman, T. G. Hill, S. L. Armour, M. van der Bunt, P. Rorsman, J. G. Knudsen, L. Briant

This study shows that reduced somatostatin signaling in mice on a high fat diet leads to increased glucagon secretion, contributing to hyperglucagonaemia.

bioRxiv · Apr 7, 2020Cell Biology

The structural basis of lipid scrambling and inactivation in the endoplasmic reticulum scramblase TMEM16K

S. R. Bushell, A. C. W. Pike, M. E. Falzone, N. J. G. Rorsman, C. M. Ta, R. A. Corey, T. D. Newport, C. A. Shintre, A. Tessitore, A. Chu, Q. Wang, L. Shrestha, S. Mukhopadhyay, J. D. Love, N. A. Burgess-Brown, , E. P. Carpenter

This study identifies TMEM16K as an ER-resident calcium-regulated lipid scramblase and elucidates its structural basis for lipid scrambling and inactivation.

bioRxiv · Dec 12, 2018Biochemistry