Author

A. Spigelman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

P. MacDonald· 2 shared A. Bautista· 1 shared A. Benrick· 1 shared A. Kim· 1 shared B. B. Lowell· 1 shared C. Miranda· 1 shared F. K. Knop· 1 shared G. Erikson· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersCell Biology

P. MacDonald

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Arginine-vasopressin mediates counter-regulatory glucagon release and is diminished in type 1 diabetes

A. Kim, J. G. Knudsen, J. C. Madara, A. Benrick, T. Hill, L. Abdul Kadir, J. A. Kellard, L. Mellander, C. Miranda, H. Lin, T. James, K. Suba, A. Spigelman, Y. Wu, P. MacDonald, , L. Briant

This study identifies arginine-vasopressin as a systemic regulator of glucagon secretion, showing its role in counter-regulatory responses to hypoglycemia and its impairment in type 1 diabetes.

bioRxiv · Jan 30, 2020Cell Biology

Aging of human endocrine pancreatic cell types is heterogeneous and sex-specific

R. Arrojo e Drigo, G. Erikson, S. Tyagi, J. Capitanio, J. Lyon, A. Spigelman, A. Bautista, J. E. Manning Fox, M. Shokhirev, P. MacDonald, M. Hetzer

This study analyzes age-related changes in human endocrine pancreatic cell types, finding sex-specific and cell-type-specific effects of aging on beta cell function and transcriptional profiles.

bioRxiv · Aug 8, 2019 · PreprintPhysiology