Author

J. G. Marques

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1

Frequent Co-Authors

M. G. Filbin· 2 shared A. G. Henssen· 1 shared A. Harmelin· 1 shared A. J. De Micheli· 1 shared B. Englinger· 1 shared B. Shim· 1 shared B. W. Schäfer· 1 shared D. Gürgen· 1 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersCancer Biology

M. G. Filbin

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Author profile →

3 papers

Recent·Most cited

Single-cell mapping of tumor heterogeneity in pediatric rhabdomyosarcoma reveals developmental signatures with therapeutic relevance

S. G. Danielli, E. Porpiglia, A. J. De Micheli, N. Navarro, M. J. Zellinger, I. Bechtold, S. Kisele, L. Volken, J. G. Marques, S. Kasper, P. K. Bode, A. G. Henssen, D. Gürgen, J. Roma, P. Bühlmann, , B. W. Schäfer

This study maps tumor heterogeneity in pediatric rhabdomyosarcoma using single-cell data, revealing developmental signatures and identifying the RAS pathway as a therapeutic target.

bioRxiv · Apr 20, 2022 · PreprintCancer Biology

VRK1 is required in VRK2-methylated cancers of the nervous system

J. So, N. Mabe, B. Englinger, M. Trissal, D. Jeong, E. A. Panditharatna, J. G. Marques, H. Justin, J. Kwon, S. M. Moyer, B. Shim, D. L. Mayhew, K. Stegmaier, M. G. Filbin, W. C. Hahn

The paper identifies VRK1 as a synthetic lethal target in VRK2-methylated nervous system cancers through CRISPR screens and functional studies.

bioRxiv · Dec 28, 2021 · PreprintCancer Biology

Single-cell epigenetic analysis reveals principles of chromatin states in H3.3-K27M gliomas

N. Harpaz, T. Mittelman, O. Beresh, O. Griess, N. Furth, T. M. Salame, R. Oren, L. Fellus-Alyagor, A. Harmelin, S. Alexandrescu, J. G. Marques, M. G. Filbin, G. Ron, E. Shema

The paper uses CyTOF to analyze histone modifications in DIPG tumors, identifying two epigenetically distinct subpopulations with differential proliferation and marker expression.

bioRxiv · Nov 2, 2021Cancer Biology