Author

N. Navarro

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 3 Cancer Biology· 3 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:human· 3 Approach:statistical model· 3 Approach:deep learning· 2 Research Focus:differential expression· 2 Assay:bulk RNA-seq· 1 Organism:Drosophila· 1

Frequent Co-Authors

J. Roma· 3 shared M. P. Landry· 3 shared S. Jeong· 3 shared G. Pons· 2 shared J. Adams· 2 shared J. Sanchez de Toledo· 2 shared J. Sansa-Girona· 2 shared L. Garcia-Gilabert· 2 shared

Activity by Year

2021-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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Curved chords = mutual co-authorship

3 shared papersCancer Biology

J. Roma

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Predicting Serotonin Detection with DNA-Carbon Nanotube Sensors Across Multiple Spectral Wavelengths

P. Kelich, J. Adams, S. Jeong, N. Navarro, M. P. Landry, L. Vukovic

The paper uses machine learning to predict serotonin detection by DNA-SWNT sensors across multiple wavelengths, showing DNA sequence's key role and limitations due to dataset size.

bioRxiv · Jan 6, 2024Bioengineering

Wing shape evolution is not constrained by ancestral genetic covariances in the invasive Drosophila suzukii

A. Fraimout, S. Chantepie, N. Navarro, C. Teplitsky, V. Debat

This study examines genetic covariance matrix stability in Drosophila suzukii during invasion, finding moderate genetic differentiation and low genetic constraint on wing shape evolution.

bioRxiv · Jan 2, 2024Evolutionary Biology

TRIB3 silencing promotes the downregulation of Akt pathway and PAX3-FOXO1 in high-risk rhabdomyosarcoma

G. O. Gallo-Oller, G. Pons, J. Sansa-Girona, N. Navarro, P. Zarzosa, L. Garcia-Gilabert, P. Cabre Fernandez, G. Guillen Barrieza, L. Valero-Arrese, M. F. Segura, J. M. Lizcano, J. Sanchez de Toledo, L. Moreno, S. Gallego, J. Roma

This study shows TRIB3 silencing reduces Akt pathway activity and PAX3-FOXO1 levels in high-risk rhabdomyosarcoma, leading to decreased tumor growth and improved survival.

bioRxiv · Dec 1, 2023Cancer Biology

Analysis of cancer genomic amplifications identifies druggable collateral dependencies within the amplicon

G. Pons, G. Gallo-Oller, N. Navarro, P. Zarzosa, J. Sansa-Girona, L. Garcia-Gilabert, A. Magdaleno, M. F. Segura, J. Sanchez de Toledo, S. Gallego, L. Moreno, J. Roma

The paper identifies druggable collateral dependencies in cancer genomic amplifications using CRISPR/Cas9 screens and integrates gene dependency with druggability and subcellular location data.

bioRxiv · Nov 16, 2022Cancer Biology

Near Infrared Nanosensors Enable Optical Imaging of Oxytocin with Selectivity over Vasopressin in Acute Mouse Brain Slices

N. Navarro, S. Jeong, N. Ouassil, J. Mun, E. Leem, M. P. Landry

This study develops a near-infrared nanosensor to selectively image oxytocin in mouse brain slices, revealing release sites with a median size of 3 micrometers.

bioRxiv · Oct 5, 2022 · PreprintBioengineering

Single-cell mapping of tumor heterogeneity in pediatric rhabdomyosarcoma reveals developmental signatures with therapeutic relevance

S. G. Danielli, E. Porpiglia, A. J. De Micheli, N. Navarro, M. J. Zellinger, I. Bechtold, S. Kisele, L. Volken, J. G. Marques, S. Kasper, P. K. Bode, A. G. Henssen, D. Gürgen, J. Roma, P. Bühlmann, , B. W. Schäfer

This study maps tumor heterogeneity in pediatric rhabdomyosarcoma using single-cell data, revealing developmental signatures and identifying the RAS pathway as a therapeutic target.

bioRxiv · Apr 20, 2022 · PreprintCancer Biology

Machine learning enables discovery of DNA-carbon nanotube sensors for serotonin

P. Kelich, S. Jeong, N. Navarro, J. Adams, X. Sun, H. Zhao, M. P. Landry, L. Vukovic

The paper uses machine learning to predict DNA sequences that create strong optical responses to serotonin in DNA-carbon nanotube sensors, discovering five new sensors with improved performance.

bioRxiv · Aug 20, 2021 · PreprintBioengineering