Author

A. J. De Micheli

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Cell Biology· 3

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Research Focus:cell type annotation· 5 Approach:deep learning· 4 Assay:scRNA-seq· 4 Approach:statistical model· 4 Organism:mouse· 3 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2 Organism:human· 2

Frequent Co-Authors

B. D. Cosgrove· 5 shared A. Flesken-Nikitin· 2 shared D.-J. Fu· 2 shared O. Elemento· 2 shared A. G. Henssen· 1 shared A. Nikitin· 1 shared A. P. Armstrong· 1 shared A. Y. Nikitin· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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5 shared papersCell Biology

B. D. Cosgrove

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Author profile →

6 papers

Recent·Most cited

Pre-ciliated tubal epithelial cells are prone to initiation of high-grade serous ovarian carcinoma

A. Flesken-Nikitin, C. Q. Ralston, D.-J. Fu, A. J. De Micheli, D. J. Phuong, B. A. Harlan, A. P. Armstrong, D. McKellar, S. Ghuwalewala, J. C. Schimenti, B. D. Cosgrove, A. Y. Nikitin

The paper identifies pre-ciliated tubal epithelial cells as a cancer-prone state in high-grade serous ovarian carcinoma by analyzing mouse uterine tube cell states and lineage dynamics.

bioRxiv · Dec 12, 2023Cancer Biology

PAX8 expressing epithelial cells are a cancer-prone source of clonal cyclical regeneration of endometrial epithelium

D.-J. Fu, A. J. De Micheli, M. Bidarimath, L. Ellenson, B. D. Cosgrove, A. Flesken-Nikitin, A. Nikitin

The paper was withdrawn due to authorship issues and should not be cited.

bioRxiv · Jun 7, 2023Cancer Biology

Single-cell mapping of tumor heterogeneity in pediatric rhabdomyosarcoma reveals developmental signatures with therapeutic relevance

S. G. Danielli, E. Porpiglia, A. J. De Micheli, N. Navarro, M. J. Zellinger, I. Bechtold, S. Kisele, L. Volken, J. G. Marques, S. Kasper, P. K. Bode, A. G. Henssen, D. Gürgen, J. Roma, P. Bühlmann, , B. W. Schäfer

This study maps tumor heterogeneity in pediatric rhabdomyosarcoma using single-cell data, revealing developmental signatures and identifying the RAS pathway as a therapeutic target.

bioRxiv · Apr 20, 2022 · PreprintCancer Biology

Single-cell Transcriptomics Identify Extensive Heterogeneity in the Cellular Composition of Mouse Achilles Tendons

A. J. De Micheli, J. B. Swanson, N. P. Disser, L. M. Martinez, N. R. Walker, D. J. Oliver, B. D. Cosgrove, C. L. Mendias

The paper uses single-cell RNA sequencing to identify 11 cell types in mouse Achilles tendons, including three new fibroblast populations, and models cell interactions.

bioRxiv · Apr 2, 2020Cell Biology

A reference single-cell transcriptomic atlas of human skeletal muscle tissue reveals bifurcated muscle stem cell populations

A. J. De Micheli, J. A. Spector, O. Elemento, B. D. Cosgrove

This study creates a single-cell transcriptomic atlas of human skeletal muscle, identifying two distinct muscle stem cell subpopulations with different transcriptional profiles and disease associations.

bioRxiv · Jan 21, 2020Cell Biology

Single-cell analysis of the muscle stem cell hierarchy identifies heterotypic communication signals involved in skeletal muscle regeneration

A. J. De Micheli, P. Fraczek, S. Soueid-Baumgarten, H. Ravichandran, I. De Vlaminck, O. Elemento, B. D. Cosgrove

This study uses scRNA-seq to map muscle stem cell hierarchy and identifies heterotypic communication signals during skeletal muscle regeneration.

bioRxiv · Jun 17, 2019Cell Biology