Author

L. Fellus-Alyagor

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Approach:experimental assay· 3 Organism:human· 3 Organism:mouse· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

R. Oren· 3 shared A. Harmelin· 2 shared E. Shema· 2 shared G. Ron· 2 shared N. Furth· 2 shared O. Golani· 2 shared A. A. Schaffer· 1 shared A. Brandis· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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3 shared papersCancer Biology

R. Oren

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Dual Targeting of Histone Deacetylases and MYC as Potential Treatment Strategy for H3-K27M Pediatric Gliomas

D. Algranati, R. Oren, B. Dassa, L. Fellus-Alyagor, A. Plotnikov, H. Barr, A. Harmelin, N. London, G. Ron, N. Furth, E. Shema

This study investigates dual targeting of HDACs and MYC in H3-K27M pediatric gliomas, showing synergistic effects in reducing cell viability and tumor growth.

bioRxiv · Feb 5, 2024Cancer Biology

Temporal genomic analysis of melanoma rejection identifies regulators of tumor immune evasion

S. C. Shvefel, J. Pai, Y. Cao, L. Pal, R. Levy, W. Yao, K. Cheng, M. Zemanek, O. Bartok, C. Weller, Y. Yin, P. Du, E. Yakubovich, I. Orr, S. Ben-Dor, , Y. Samuels

The paper identifies Mif as a regulator of tumor immune evasion in low intra-tumor heterogeneity melanoma by analyzing single-cell RNA sequencing data and validating in patient data.

bioRxiv · Nov 29, 2023 · PreprintCancer Biology

The differential regulation of placenta trophoblast bisphosphoglycerate mutase in fetal growth restriction: preclinical study in mice and observational histological study of human placenta.

S. Stroganov, T. Harris, L. Fellus-Alyagor, L. Ben Moyal, R. Plitman Mayo, O. Golani, A. Brandis, T. Mehlman, M. Kovo, T. Biron-Shental, N. Dekel, M. Neeman

This study investigates the role of placental BPGM in fetal growth restriction using mouse models and human placental analysis, finding altered BPGM expression and 2,3 BPG levels in hypoxic conditions.

bioRxiv · Sep 14, 2022Physiology

Single-cell epigenetic analysis reveals principles of chromatin states in H3.3-K27M gliomas

N. Harpaz, T. Mittelman, O. Beresh, O. Griess, N. Furth, T. M. Salame, R. Oren, L. Fellus-Alyagor, A. Harmelin, S. Alexandrescu, J. G. Marques, M. G. Filbin, G. Ron, E. Shema

The paper uses CyTOF to analyze histone modifications in DIPG tumors, identifying two epigenetically distinct subpopulations with differential proliferation and marker expression.

bioRxiv · Nov 2, 2021Cancer Biology