Optimization of host cell-compatible, antimicrobial peptides effective against biofilms and clinical isolates of drug-resistant bacteria.
J. Ghimire, R. J. Hart, A. Soldano, C. Chen, S. Guha, J. P. Hoffmann, K. Hall, L. Sun, B. J. Nelson, T. K. Lu, J. K. Kolls, M. Rivera, L. A. Morici, W. C. Wimley
This study optimizes antimicrobial peptides to enhance activity against drug-resistant bacteria and biofilms while reducing cytotoxicity.
bioRxiv · Dec 1, 2022Biochemistry