Author

J. H. Ruth

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Biology Disciplines

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Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

A. Sawalha· 1 shared D. A. Fox· 1 shared D. Khanna· 1 shared D. M. Rohraff· 1 shared E. N. Model· 1 shared J. L. Hervoso· 1 shared M. A. Amin· 1 shared M. Ali· 1 shared

Activity by Year

2020-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperPharmacology & Toxicology

A. Sawalha

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1 paper

Recent·Most cited

Inhibition of histone readers bromodomain extra-terminal proteins alleviates skin fibrosis in experimental models of scleroderma

S. Vichaikul, M. Gurrea-Rubio, M. A. Amin, P. L. Campbell, Q. Wu, M. N. Mattichak, W. D. Brodie, P. J. Palisoc, M. Ali, S. Muraoka, J. H. Ruth, E. N. Model, D. M. Rohraff, J. L. Hervoso, Y. Mao-Draayer, , P.-S. Tsou

This study shows that inhibiting BET proteins, particularly BRD4, reduces skin fibrosis in scleroderma models by affecting calcium signaling and gene expression.

bioRxiv · Aug 7, 2020Pharmacology & Toxicology