Author

J. H. Sinclair

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

E. G. Elder· 1 shared E. Y. Lim· 1 shared M. J. Smit· 1 shared M. Wills· 1 shared R. Heukers· 1 shared T. W. M. De Groof· 1 shared

Activity by Year

2021-2021 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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1 shared paperMicrobiology

E. G. Elder

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1 paper

Recent·Most cited

Targeting the latent human cytomegalovirus reservoir with virus specific nanobodies

T. W. M. De Groof, E. G. Elder, R. Heukers, E. Y. Lim, M. Wills, J. H. Sinclair, M. J. Smit

This study develops a nanobody that partially inhibits HCMV receptor signaling and enhances T-cell killing of latently infected monocytes, offering a potential therapy for clearing HCMV reservoirs in transplant patients.

Nature Communications · Jul 21, 2021Peer-reviewedMicrobiology