Author

T. W. M. De Groof

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Biology Disciplines

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Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

E. G. Elder· 1 shared E. Y. Lim· 1 shared J. H. Sinclair· 1 shared M. J. Smit· 1 shared M. Wills· 1 shared R. Heukers· 1 shared

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2021-2021 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperMicrobiology

E. G. Elder

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1 paper

Recent·Most cited

MicrobiologyNature CommunicationsPeer-reviewedJul 21, 2021

Targeting the latent human cytomegalovirus reservoir with virus specific nanobodies

T. W. M. De Groof, E. G. Elder, R. Heukers…·M. J. Smit

This study develops a nanobody that partially inhibits HCMV receptor signaling and enhances T-cell killing of latently infected monocytes, offering a potential therapy for clearing HCMV reservoirs in transplant patients.

DOI 10.1038/s41467-021-24608-5

humanproteomics

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