Author

J. Hauenstein

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

A.-S. Johansson· 2 shared C. Gustafsson· 2 shared E. Somuncular· 2 shared R. Mansson· 2 shared S. Luc· 2 shared A. Forlani· 1 shared A. Krstic· 1 shared C. Dahlberg· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersCell Biology

A.-S. Johansson

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2 papers

Recent·Most cited

Aging is associated with functional and molecular changes in distinct hematopoietic stem cell subsets

E. Somuncular, J. Hauenstein, T.-Y. Su, O. Dumral, C. Gustafsson, E. Tzortzis, A. Forlani, A.-S. Johansson, R. Mansson, S. Luc

This study shows that aging causes functional and molecular changes in distinct hematopoietic stem cell subsets, including increased myeloid differentiation and age-dependent gene expression changes.

bioRxiv · Aug 8, 2023 · PreprintCell Biology

FOXO dictates initiation of B cell development and myeloid restriction in common lymphoid progenitors

L. Pena-Perez, S. Kharazi, N. Frengen, A. Krstic, T. Bouderlique, J. Hauenstein, M. He, E. Somuncular, X. Li Wang, C. Dahlberg, C. Gustafsson, A.-S. Johansson, J. Walfridsson, N. Kadri, P. S. Woll, , R. Mansson

The paper shows that FOXO1 and FOXO3 are essential for B cell development and myeloid restriction in common lymphoid progenitors, with their combined loss causing developmental block and loss of B cell lineage.

bioRxiv · Jan 21, 2022Immunology