Author

P. S. Woll

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 2 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Research Focus:differential expression· 2 Organism:human· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

S. E. W. Jacobsen· 3 shared A. Castor· 1 shared A. Ho· 1 shared A. J. Mead· 1 shared A. Krstic· 1 shared A. M. Lord· 1 shared A. Marciniak-Czochra· 1 shared A. Schuh· 1 shared

Activity by Year

2022-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersCancer Biology

S. E. W. Jacobsen

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Erythroid differentiation intensifies RNA mis-splicing in SF3B1-mutant myelodysplastic syndromes with ring sideroblasts

P. L. Moura, T. Mortera-Blanco, I. J. F. Hofman, G. Todisco, W. W. Kretzschmar, A.-C. Bjorklund, M. Creignou, M. Hagemann-Jensen, C. Ziegenhain, D. C. Granados, I. Barbosa, G. Walldin, M. Jansson, N. Ashley, A. J. Mead, , E. Hellstrom-Lindberg

This study investigates SF3B1-mutant myelodysplastic syndromes with ring sideroblasts by isolating RS and analyzing their development and mis-splicing during erythroid differentiation.

bioRxiv · Apr 11, 2023Cancer Biology

Parallel clonal and molecular profiling of hematopoietic stem cells using RNA barcoding

E. E. Wojtowicz, J. Mistry, V. Uzun, A. Scoones, D. V. Chin, L. Kettyle, F. Grasso, A. M. Lord, G. Etherington, C. Hellmich, P. S. Woll, M. E. Belderbos, K. M. Bowles, C. Nerlov, W. Haerty, , I. C. Macaulay

This study uses RNA barcoding and single-cell RNA-seq to analyze clonal dynamics of hematopoietic stem cells, showing that platelet depletion shifts HSC output to platelets and new myeloid clones.

bioRxiv · May 16, 2022 · PreprintCell Biology

Complex genotype-phenotype relationships shape the response to treatment of Down Syndrome Childhood Acute Lymphoblastic Leukaemia

C. Lutz, V. A. Turati, R. Clifford, P. S. Woll, T. Stiehl, A. Castor, S. A. Clark, H. Ferry, V. Buckle, A. Trumpp, A. Ho, A. Marciniak-Czochra, J. Herrero, A. Schuh, S. E. W. Jacobsen, T. Enver

This study investigates genotype-phenotype relationships in Down Syndrome ALL, showing that genetic and phenotypic heterogeneity influences treatment response and relapse through clonal competition.

bioRxiv · Feb 6, 2022Cancer Biology

FOXO dictates initiation of B cell development and myeloid restriction in common lymphoid progenitors

L. Pena-Perez, S. Kharazi, N. Frengen, A. Krstic, T. Bouderlique, J. Hauenstein, M. He, E. Somuncular, X. Li Wang, C. Dahlberg, C. Gustafsson, A.-S. Johansson, J. Walfridsson, N. Kadri, P. S. Woll, , R. Mansson

The paper shows that FOXO1 and FOXO3 are essential for B cell development and myeloid restriction in common lymphoid progenitors, with their combined loss causing developmental block and loss of B cell lineage.

bioRxiv · Jan 21, 2022Immunology