Author

J. Iovanna

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 4

Signature Assays, Organisms & Methods

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Organism:human· 4 Research Focus:cell type annotation· 3 Approach:experimental assay· 2 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1 Research Focus:differential expression· 1

Frequent Co-Authors

C. Neuzillet· 3 shared N. J. Dusetti· 3 shared R. Nicolle· 3 shared F. Delecourt· 2 shared J. Cros· 2 shared J. Raffenne· 2 shared L. De Mestier· 2 shared M. Ayadi· 2 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCancer Biology

C. Neuzillet

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4 papers

Recent·Most cited

Redefining phenotypic intratumor heterogeneity of pancreatic ductal adenocarcinoma: a bottom-up approach

M. Hilmi, F. Delecourt, J. Raffenne, T. Bourega, N. J. Dusetti, J. Iovanna, Y. Blum, M. Richard, C. Neuzillet, A. Couvelard, L. De Mestier, V. Rebours, R. Nicolle, J. Cros

The paper develops an immunohistochemical panel to assess intra- and inter-tumoral heterogeneity in PDAC, identifying four distinct phenotypes with clinical implications.

bioRxiv · Nov 16, 2023Cancer Biology

PACpAInt: a deep learning approach to identify molecular subtypes of pancreatic adenocarcinoma on histology slides

C. Saillard, F. Delecourt, B. Schmauch, O. Moindrot, M. Svrcek, A. Bardier-Dupas, J.-F. Emile, M. Ayadi, V. Rebours, L. de Mestier, P. Hammel, C. Neuzillet, J.-B. Bachet, J. Iovanna, N. Dusetti, , J. Cros

PACpAInt uses deep learning to identify molecular subtypes of pancreatic adenocarcinoma on histology slides, revealing prognostic heterogeneity and novel subtypes.

bioRxiv · Jan 4, 2022 · PreprintCancer Biology

Translatome-based classification reveals a dual metabolic dependency of a new tumor subtype of pancreatic cancer.

S. Shin, R. Nicolle, C. Jean, R. Samain, M. Ayadi, J. Raffenne, A. Brunel, J. Solorzano, C. Neuzillet, C. Joffre, S. Rocchi, J. Iovanna, N. J. Dusetti, O. Larsson, S. Pyronnet, , Y. Martineau

The paper identifies a new pancreatic cancer subtype with low protein synthesis but high integrated stress response activation, linked to metabolic impairments and drug resistance.

bioRxiv · Dec 23, 2020Cancer Biology

E-cadherin is a structuring component of invadopodia in pancreatic cancer

A. Dobric, S. Germain, F. Silvy, R. Bonier, S. Audebert, L. Camoin, N. J. Dusetti, P. Soubeyran, J. Iovanna, V. Rigot, F. Andre

This study identifies E-cadherin as a critical structural component of invadopodia in pancreatic cancer cells, showing its role in invadopodia formation and structuration through interactions with Arp2/3, Cortactin, and MT1-MMP.

bioRxiv · Oct 9, 2020Cancer Biology