BiochemistrybioRxiv
Flexibility and distributive synthesis regulate RNA priming and handoff in human DNA polymerase α-primase
J. J. Cordoba, E. A. Mullins, L. E. Salay…·W. J. Chazin
This study investigates RNA primer synthesis and handoff in human DNA polymerase α-primase, showing that flexibility and distributive synthesis are key to primer generation and transfer.
DOI 10.1016/j.jmb.2023.168330