Author

J. J. Krolewski

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Assay:imaging· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

K. L. Nastiuk· 4 shared S. Singh· 4 shared C. Pan· 3 shared K. H. Eng· 3 shared K. Sha· 3 shared R. Zhang· 3 shared A. Maolake· 2 shared B. Xu· 2 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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4 shared papersCancer Biology

K. L. Nastiuk

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4 papers

Recent·Most cited

Androgen deprivation triggers a cytokine signaling switch to induce immune suppression and prostate cancer recurrence

K. Sha, R. Zhang, A. Maolake, S. Singh, G. Chatta, K. H. Eng, K. L. Nastiuk, J. J. Krolewski

bioRxiv · Dec 1, 2023 · PreprintCancer Biology

Stromal resistance to castration-induced prostate regression in a mouse model of benign prostatic hyperplasia

R. Zhang, S. Singh, C. Pan, B. Xu, J. Kindblom, S.-Y. Yeh, C. Chang, K. H. Eng, J. J. Krolewski, K. L. Nastiuk

This study shows that stromal compartments in a mouse model of BPH are resistant to castration-induced regression, suggesting the need for additional therapies.

bioRxiv · Dec 7, 2022 · PreprintPathology

TNF signaling is required for castration-induced vascular damage preceding prostate cancer regression

J. J. Krolewski, S. Singh, K. Sha, N. Jaiswal, S. G. Turowski, C. Pan, L. J. Rich, M. Seshadri, K. L. Nastiuk

This study shows TNF signaling is required for castration-induced vascular damage in prostate cancer, which contributes to tumor regression.

bioRxiv · Feb 5, 2022 · PreprintCancer Biology

Glucocorticoid signaling delays castration-induced regression in murine models of prostate cancer

A. Maolake, R. Zhang, K. Sha, S. Singh, C. Pan, B. Xu, G. Chatta, M. Mastri, K. H. Eng, J. J. Krolewski, K. L. Nastiuk

This study shows that glucocorticoid signaling delays castration-induced regression in murine prostate cancer models by maintaining tumor proliferation through GR activation, which can be blocked by the GR antagonist relacorilant.

bioRxiv · Oct 11, 2021 · PreprintCancer Biology