Author

J. J. Rochford

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 1 Physiology· 1

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1

Frequent Co-Authors

G. D. Mcilroy· 2 shared A. Roumane· 1 shared D. Thompson· 1 shared L. K. Heisler· 1 shared N. Mody· 1 shared N. Sommer· 1 shared N. Z. Morrice· 1 shared P. D. Whitfield· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersPhysiology

G. D. Mcilroy

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2 papers

Recent·Most cited

Hydroxysteroid 17-beta dehydrogenase 13 (Hsd17b13) knockdown attenuates liver steatosis in high-fat diet obese mice

S. Mahmood, N. Z. Morrice, D. Thompson, S. Milanizadeh, S. Wilson, P. D. Whitfield, G. D. Mcilroy, J. J. Rochford, N. Mody

This study shows that knocking down Hsd17b13 in obese mice reduces liver steatosis and improves liver health markers, suggesting HSD17B13 as a therapeutic target for MASLD.

bioRxiv · Feb 27, 2024 · PreprintPhysiology

GLP-1 Receptor Agonist Improves Metabolic Disease in a Pre-clinical Model of Lipodystrophy

A. Roumane, G. D. Mcilroy, N. Sommer, W. Han, L. K. Heisler, J. J. Rochford

This study shows that liraglutide, a GLP-1R agonist, improves metabolic disease in seipin knockout mice, a model of lipodystrophy, by enhancing insulin secretion and reducing liver fibrosis.

bioRxiv · Sep 1, 2023Pharmacology & Toxicology