Author

N. Sommer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Assay:metabolomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. Fazio· 1 shared A. Roumane· 1 shared A. Walker· 1 shared A. Wolf· 1 shared B. Stecher· 1 shared C. Kaleta· 1 shared C. Malainou· 1 shared D. Bordoni· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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1 shared paperImmunology

A. Fazio

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

GLP-1 Receptor Agonist Improves Metabolic Disease in a Pre-clinical Model of Lipodystrophy

A. Roumane, G. D. Mcilroy, N. Sommer, W. Han, L. K. Heisler, J. J. Rochford

This study shows that liraglutide, a GLP-1R agonist, improves metabolic disease in seipin knockout mice, a model of lipodystrophy, by enhancing insulin secretion and reducing liver fibrosis.

bioRxiv · Sep 1, 2023Pharmacology & Toxicology

Cell-type-specific efferocytosis determines functional plasticity of alveolar macrophages

J. Better, M. Wetstein, M. Estiri, C. Malainou, M. R. Ferrero, M. Langelage, I. Kuznetsova, I. Vazquez-Armendariz, L. Kimmig, S. Mansouri, R. Savai, J. Wilhelm, I. Alexopoulos, N. Sommer, S. Herold, U. Matt

Neutrophil efferocytosis reprograms mitochondrial metabolism to switch alveolar macrophages to a pro-resolution phenotype at the cost of bacterial control.

bioRxiv · Mar 7, 2023Immunology

Microbial regulation of hexokinase 2 links mitochondrial metabolism and cell death in colitis

J. Hamm, F. Hinrichsen, L. Schroder, N. Mishra, K. Shima, A. Walker, N. Sommer, K. Klischies, D. Prasse, J. Zimmermann, S. Kaiser, D. Bordoni, A. Fazio, G. Laue, V. Tremaroli, , F. Sommer

This study shows that microbial regulation of HK2 links mitochondrial metabolism and cell death in colitis, with butyrate protecting against inflammation by repressing HK2.

bioRxiv · Dec 22, 2020Immunology