Design of optical imaging probes by screening of diverse substrate libraries directly in disease tissue extracts
M. Tholen, J. J. Yim, K. Groborz, E. Yoo, B. A. Martin, N. S. van den Berg, M. Drag, M. Bogyo
The paper develops fluorescent probes for cancer detection by screening peptide libraries in tissue extracts, identifying highly effective tumor-specific probes that outperform previous designs.
bioRxiv · Jun 8, 2020Bioengineering