Author

J. K. Liang

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Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Assay:ATAC-seq· 1 Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

B. Liau· 1 shared D. D. Hwang· 1 shared E. M. Garcia· 1 shared J. Woods· 1 shared N. Z. Lue· 1 shared W. K. Lieberman· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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1 shared paperBiochemistry

B. Liau

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1 paper

Recent·Most cited

Base Editor Scanning Reveals Activating Mutations of DNMT3A

E. M. Garcia, N. Z. Lue, J. K. Liang, W. K. Lieberman, D. D. Hwang, J. Woods, B. Liau

The paper uses base editor mutagenesis to identify activating DNMT3A mutations, revealing hyperactivating variants in the ADD domain that remain functional in the presence of a heterozygous R882H mutation.

bioRxiv · Apr 12, 2023Biochemistry