Molecular basis of human asparagine synthetase inhibitor specificity
W. Zhu, A. Radadiya, C. Bisson, B. Nordin, P. Baumann, T. Imasaki, S. Wenzel, S. Sedelnikova, A. Berry, T. Nomanbhoy, J. Kozarich, Y. Jin, Y. Takagi, D. Rice, N. Richards
The paper determines the X-ray crystal structure of human ASNS and builds a computational model of the enzyme-inhibitor complex to understand specificity.
bioRxiv · Sep 29, 2018 · PreprintBiochemistry