Author

T. Imasaki

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Biophysics· 1 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Assay:structural biology· 3 Organism:human· 2 Research Focus:protein structure prediction· 2 Organism:C. elegans· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

E. Nitta· 3 shared N. Sakai· 3 shared R. Nitta· 3 shared Y. Saijo-Hamano· 3 shared H. Okuma· 2 shared H. Shigematsu· 2 shared S. Kikkawa· 2 shared S. Niwa· 2 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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3 shared papersMicrobiology

E. Nitta

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Structural basis of Irgb6 inactivation by Toxoplasma gondii through the phosphorylation of switch I.

H. Okuma, Y. Saijo-Hamano, A. A. Sherif, E. Hoshizaki, N. Sakai, T. Kato, T. Imasaki, E. Nitta, M. Sasai, Y. Maniwa, H. Kosako, D. M. Standley, M. Yamamoto, R. Nitta

The paper reveals how Toxoplasma gondii inactivates Irgb6 through ROP18-mediated phosphorylation, preventing its function in host defense.

bioRxiv · Oct 31, 2022 · PreprintMicrobiology

Structural model of microtubule dynamics inhibition by Kinesin-4 from the crystal structure of KLP-12 - tubulin complex

S. Taguchi, J. Nakano, T. Imasaki, T. Kita, Y. Saijo-Hamano, N. Sakai, H. Shigematsu, H. Okuma, T. Shimizu, E. Nitta, S. Kikkawa, S. Mizobuchi, S. Niwa, R. Nitta

The paper reports the crystal structure of KLP-12-tubulin complex, revealing how KLP-12 inhibits microtubule dynamics by altering tubulin curvature.

bioRxiv · Feb 14, 2022Biophysics

CAMSAP2 organizes a γ-tubulin-independent microtubule nucleation centre

T. Imasaki, S. Kikkawa, S. Niwa, Y. Saijo-Hamano, H. Shigematsu, K. Aoyama, K. Mitsuoka, M. Aoki, A. Sakamot, Y. Tomabechi, N. Sakai, M. Shirouz, S. Taguchi, Y. Yamagish, T. Setsu, , R. Nitta

The paper shows CAMSAP2 nucleates microtubules from soluble β-tubulin without γ-tubulin, reducing the nucleation barrier and forming aster-like structures.

bioRxiv · Mar 1, 2021 · PreprintCell Biology

A practical method for efficient and optimal production of selenomethionine-labeled recombinant protein complexes in the insect cells

S. Wenzel, T. Imasaki, Y. Takagi

This paper describes a method to efficiently produce selenomethionine-labeled recombinant protein complexes in insect cells by overcoming SeMet toxicity through baculovirus infection and TEQC.

bioRxiv · Jan 9, 2019Biochemistry

Molecular basis of human asparagine synthetase inhibitor specificity

W. Zhu, A. Radadiya, C. Bisson, B. Nordin, P. Baumann, T. Imasaki, S. Wenzel, S. Sedelnikova, A. Berry, T. Nomanbhoy, J. Kozarich, Y. Jin, Y. Takagi, D. Rice, N. Richards

The paper determines the X-ray crystal structure of human ASNS and builds a computational model of the enzyme-inhibitor complex to understand specificity.

bioRxiv · Sep 29, 2018 · PreprintBiochemistry