European sea bass rapidly regulate blood and red cell pH within 2 hours and 40 minutes, respectively, protecting O2 transport capacity via enhanced gill acid excretion.

bioRxiv · Apr 22, 2021Physiology

A virus hosted in malaria-infected blood protects against T cell-mediated inflammatory diseases by impairing DC function in a type I IFN-dependent manner

A. Hassan, M. F. Wlodarczyk, M. Benamar, E. Bassot, A. Salvioni, S. Kassem, A. Berry, A. Saoudi, N. Blanchard

This study identifies an RNA virus co-hosted in malaria parasites that protects against T cell-mediated inflammatory diseases by impairing dendritic cell function through type I IFN signaling.

bioRxiv · Nov 4, 2019Immunology

Cardiac structure and function in patients with schizophrenia taking antipsychotic drugs: an MRI study

T. Pillinger, E. Osimo, A. de Marvao, A. Berry, T. Whitehurst, B. Statton, M. Quinlan, S. Brugger, A. Vazir, S. Cook, D. O'Regan, O. Howes

This study uses MRI to compare cardiac fibrosis and function in schizophrenia patients on antipsychotics with healthy controls, finding increased T1 times and reduced cardiac volumes in patients.

bioRxiv · Mar 27, 2019Physiology

Insertion sequences drive the emergence of a highly adapted human pathogen

E. Sentausa, P. Basso, A. Berry, A. Adrait, G. Bellement, Y. Coute, S. Lory, S. Elsen, I. Attree

The paper shows that insertion sequences in Pseudomonas aeruginosa enhance virulence and antibiotic resistance in a human pathogen.

bioRxiv · Oct 25, 2018Microbiology

Molecular basis of human asparagine synthetase inhibitor specificity

W. Zhu, A. Radadiya, C. Bisson, B. Nordin, P. Baumann, T. Imasaki, S. Wenzel, S. Sedelnikova, A. Berry, T. Nomanbhoy, J. Kozarich, Y. Jin, Y. Takagi, D. Rice, N. Richards

The paper determines the X-ray crystal structure of human ASNS and builds a computational model of the enzyme-inhibitor complex to understand specificity.

bioRxiv · Sep 29, 2018 · PreprintBiochemistry