Author

N. Richards

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:structural biology· 2 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

A. Radadiya· 2 shared W. Zhu· 2 shared A. Berry· 1 shared B. Nordin· 1 shared C. Bisson· 1 shared D. Rice· 1 shared H. Liu· 1 shared J. Kozarich· 1 shared

Activity by Year

2018-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersBiochemistry

A. Radadiya

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2 papers

Recent·Most cited

Structure of the ForT/PRPP complex uncovers the mechanism of C-C bond formation in C-nucleotide antibiotic biosynthesis

S. Gao, A. Radadiya, W. Li, H. Liu, W. Zhu, V. de Crecy-Lagard, N. Richards, J. Naismith

The paper reports the structure of the ForT/PRPP complex and identifies residues critical for catalysis, proposing a mechanism for C-C bond formation in C-nucleotide antibiotic biosynthesis.

bioRxiv · Mar 26, 2020 · PreprintBiochemistry

Molecular basis of human asparagine synthetase inhibitor specificity

W. Zhu, A. Radadiya, C. Bisson, B. Nordin, P. Baumann, T. Imasaki, S. Wenzel, S. Sedelnikova, A. Berry, T. Nomanbhoy, J. Kozarich, Y. Jin, Y. Takagi, D. Rice, N. Richards

The paper determines the X-ray crystal structure of human ASNS and builds a computational model of the enzyme-inhibitor complex to understand specificity.

bioRxiv · Sep 29, 2018 · PreprintBiochemistry