Remodeling of the core leads HIV-1 pre-integration complex in the nucleus of human lymphocytes.
G. Blanco, A. Gazi, B. Monel, S. Frabetti, V. Scoca, F. Mueller, O. Schwartz, J. krijnse-locker, P. Charneau, F. Di Nunzio
This study reveals how HIV-1 CA proteins remodel into a 'pearl necklace' structure around viral DNA to facilitate nuclear entry in human lymphocytes.
Journal of Virology · May 18, 2020Peer-reviewedMicrobiology