Widespread multi-targeted therapy resistance via drug-induced secretome fucosylation
M. B. D. Aldonza, J. Cha, I. Yong, J. Ku, D. Lee, P. Sinitcyn, R.-E. Cho, R. D. Delos Reyes, D. Kim, H.-J. Sung, S. Kim, M. Kang, Y. Ku, G. Park, H. S. Ryu, , Y. Kim
This study identifies drug-induced secretome fucosylation as a mechanism of resistance to targeted therapies across multiple cancers.
bioRxiv · Apr 21, 2021 · PreprintCancer Biology