Deep and fast label-free Dynamic Organellar Mapping
J. P. Schessner, V. Albrecht, A. K. Davies, P. Sinitcyn, G. H. H. Borner
This paper introduces DIA-DOMs, a method enhancing subcellular protein localization profiling using DIA-MS, and presents DOM-QC for analysis, showing improved depth, precision, and throughput in HeLa cells.
bioRxiv · Nov 9, 2021Biochemistry