Author

J. Kurushima

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 5

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:gene regulatory network inference· 2 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1

Frequent Co-Authors

J.-W. Veening· 3 shared H. Tomita· 2 shared A. Domenech· 1 shared A.-S. Rueff· 1 shared C. M. J. E. Vandenbroucke-Grauls· 1 shared D. van de Beek· 1 shared G. Cerckel· 1 shared H. Hirakawa· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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3 shared papersMicrobiology

J.-W. Veening

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5 papers

Recent·Most cited

Enterococcal linear plasmids adapt to Enterococcus faecium and spread within multidrug-resistant clades.

Y. Hashimoto, M. Suzuki, S. Kobayashi, Y. Hirahara, T. Nomura, J. Kurushima, H. Hirakawa, K. Tanimoto, H. Tomita

This study identifies enterococcal linear plasmids that spread AMR genes through horizontal transfer and contribute to multidrug resistance in Enterococcus faecium.

bioRxiv · Sep 7, 2022 · PreprintMicrobiology

Pneumolysin promotes host cell necroptosis and bacterial competence during pneumococcal meningitis as shown by whole animal dual RNA-seq

K. K. Jim, R. Aprianto, A. Domenech, J. Kurushima, D. van de Beek, C. M. J. E. Vandenbroucke-Grauls, W. Bitter, J.-W. Veening

bioRxiv · Feb 10, 2022Microbiology

Inactivation of GalU leads the cell wall-associated polysaccharide defect to reduce the susceptibility to bacteriolytic agents in Enterococcus faecalis

J. Kurushima, H. Tomita

The paper shows that a galU mutation in Enterococcus faecalis reduces susceptibility to bacteriolytic agents by impairing cell wall polysaccharide production.

bioRxiv · Nov 20, 2020Microbiology

Unbiased homeologous recombination during pneumococcal transformation allows for multiple chromosomal integration events

J. Kurushima, N. Campo, R. van Raaphorst, G. Cerckel, P. Polard, J.-W. Veening

This study investigates pneumococcal transformation at the single-cell level, showing that multiple chromosomal integration events occur through unbiased homeologous recombination, with transformation efficiency capped at ~50%.

bioRxiv · Mar 15, 2020Microbiology

Three new integration vectors and fluorescent proteins for use in the opportunistic human pathogen Streptococcus pneumoniae

L. E. Keller, A.-S. Rueff, J. Kurushima, J.-W. Veening

This paper introduces three new integration vectors and fluorescent proteins for Streptococcus pneumoniae, enhancing genetic manipulation and visualization capabilities.

bioRxiv · Mar 31, 2019Microbiology