Author

J. L. Campbell

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 2 Approach:experimental assay· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:genome assembly· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

B. Shen· 2 shared L. Zheng· 2 shared A. Franchitto· 1 shared A. Palma· 1 shared C. A. Sedgeman· 1 shared C. Liu· 1 shared E. Malacaria· 1 shared F. A. Aiello· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersBiochemistry

B. Shen

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2 papers

Recent·Most cited

FANCD2 and RAD51 recombinase directly inhibit DNA2 nucleases at stalled replication forks and FANCD2 acts as a novel RAD51 mediator in strand exchange to promote genome stability

W. Liu, P. Polaczek, I. Roubal, Y. Meng, W.-c. Choe, M. C. Caron, C. A. Sedgeman, Y. Xi, C. Liu, Q. Wu, L. Zheng, J. Y. Masson, B. Shen, J. L. Campbell

This study shows FANCD2 inhibits DNA2 nuclease activity and stabilizes RAD51 filaments to protect stalled replication forks, promoting genome stability.

bioRxiv · Jul 8, 2021Biochemistry

RAD51 AND MITOTIC FUNCTION OF MUS81 ARE ESSENTIAL FOR RECOVERY FROM LOW-DOSE OF CAMPTOTHECIN IN THE ABSENCE OF THE WRN EXONUCLEASE

P. Pichierri, F. A. Aiello, A. Palma, E. Malacaria, L. Zheng, J. L. Campbell, B. Shen, A. Franchitto

The paper investigates how WRN exonuclease deficiency affects replication fork recovery from camptothecin, showing RAD51 and MUS81 mitotic function are essential to prevent genome instability.

bioRxiv · Aug 25, 2018Cell Biology