Author

F. A. Aiello

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 3 Approach:experimental assay· 3 Organism:human· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:cryo-EM· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

E. Malacaria· 3 shared P. Pichierri· 3 shared A. Franchitto· 2 shared G. Marozzi· 2 shared L. Di Biagi· 2 shared M. Honda· 2 shared M. Spies· 2 shared A. Palma· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersCell Biology

E. Malacaria

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

A double-ring of human RAD52 remodels replication forks restricting fork reversal

M. Honda, M. Razzaghi, P. Gaur, E. Malacaria, G. Marozzi, L. Di Biagi, F. A. Aiello, E. A. Paintsil, A. Stanfield, B. J. Deppe, L. Gakhar, N. J. Schnicker, M. A. Spies, P. Pichierri, M. Spies

The paper shows human RAD52 forms a double-ring structure around stalled replication forks, remodeling them via DNA strand exchange to prevent reversal by SMARCAL1.

bioRxiv · Nov 14, 2023 · PreprintBiochemistry

RAD52 prevents accumulation of Polα-dependent replication gaps at perturbed replication forks

G. Marozzi, L. Di Biagi, E. Malacaria, M. Honda, P. Valenzisi, F. A. Aiello, M. Spies, A. Franchitto, P. Pichierri

This study shows RAD52 prevents Polα-dependent replication gaps by enabling RAD51/Pol repriming at reversed replication forks, which limits DNA damage and improves cell viability during replication stress.

bioRxiv · Apr 12, 2023 · PreprintCell Biology

RAD51 AND MITOTIC FUNCTION OF MUS81 ARE ESSENTIAL FOR RECOVERY FROM LOW-DOSE OF CAMPTOTHECIN IN THE ABSENCE OF THE WRN EXONUCLEASE

P. Pichierri, F. A. Aiello, A. Palma, E. Malacaria, L. Zheng, J. L. Campbell, B. Shen, A. Franchitto

The paper investigates how WRN exonuclease deficiency affects replication fork recovery from camptothecin, showing RAD51 and MUS81 mitotic function are essential to prevent genome instability.

bioRxiv · Aug 25, 2018Cell Biology