IRF7 from the black flying fox induces a STAT1-independent ISG response in unstimulated cell lines that protects against diverse RNA viruses
P. C. De La Cruz-Rivera, J. L. Eitson, J. W. Schoggins
This study identifies IRF7 from the black flying fox as a potent antiviral molecule that induces an ISG response independent of STAT1, providing broad protection against multiple RNA viruses.
bioRxiv · May 2, 2024 · PreprintImmunology