Author

J. L. Golob

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

J. Y. Kao· 3 shared N. Kamada· 3 shared S. Bishu· 3 shared A. Lee· 2 shared G. Hou· 2 shared H. Grasberger· 2 shared A. Nusrat· 1 shared A. Rosevelt· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersImmunology

J. Y. Kao

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Author profile →

4 papers

Recent·Most cited

Inflammation induced Th17 cells synergize with the inflammation-trained microbiota to mediate host-resiliency against intestinal injury

J. L. Golob, G. Hou, B. Swanson, S. Bishu, H. Grasberger, M. El-Zaatari, A. Lee, J. Y. Kao, N. Kamada, S. Bishu

The paper shows that transient inflammation generates protective Th17 cells that work with trained microbiota to protect against intestinal injury.

bioRxiv · Mar 25, 2024Immunology

IL-15 promotes inflammatory Th17 cells in the intestine

J. L. Golob, G. Hou, A. Lee, H. Grasberger, E. Berinstein, M. E. Zaatari, V. Khaykin, J. Berinstein, C. Fry, J. Nemzek, N. Kamada, J. Y. Kao, S. Bishu

The paper shows IL-15 promotes inflammatory Th17 cells in the intestine by upregulating RORC via JAK1 in TRM, suggesting IL-15 as a potential therapeutic target for UC.

bioRxiv · Mar 11, 2023 · PreprintImmunology

Mucolytic bacteria license pathobionts to acquire host-derived nutrients during dietary nutrient restriction

K. Sugihara, S. Kitamoto, P. Saraithong, H. Nagao-Kitamoto, C. McCarthy, M. Hoostal, A. Rosevelt, C. K. Muraleedharan, M. G. Gillilland, J. Imai, M. Omi, S. Bishu, J. Y. Kao, C. Alteri, N. Barnich, , N. Kamada

The paper shows that mucolytic bacteria enable pathobionts to acquire host-derived nutrients during dietary restriction, allowing them to thrive in the gut.

bioRxiv · Jan 17, 2022Microbiology

Comparative analysis of public RNA-sequencing data from human intestinal enteroid (HIEs) infected with enteric RNA viruses identifies universal and virus-specific epithelial responses

R. J. Cieza, J. L. Golob, J. A. Colacino, C. E. Wobus

The paper analyzes public RNA-seq data from HIEs infected with enteric viruses to identify common and virus-specific epithelial responses.

bioRxiv · Mar 30, 2021Microbiology