Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
7 papers
Recent·Most cited
J. L. Golob, G. Hou, B. Swanson, S. Bishu, H. Grasberger, M. El-Zaatari, A. Lee, J. Y. Kao, N. Kamada, S. Bishu
The paper shows that transient inflammation generates protective Th17 cells that work with trained microbiota to protect against intestinal injury.
bioRxiv · Mar 25, 2024Immunology
M. M. Elmassry, K. Sugihara, P. Chankhamjon, F. R. Camacho, S. Wang, Y. Sugimoto, S. Chatterjee, L. A. Chen, N. Kamada, M. S. Donia
This study identifies disease-associated small molecules from the gut microbiome of IBD patients using metagenomic analysis and synthetic biology.
bioRxiv · Feb 7, 2024Microbiology
J. L. Golob, G. Hou, A. Lee, H. Grasberger, E. Berinstein, M. E. Zaatari, V. Khaykin, J. Berinstein, C. Fry, J. Nemzek, N. Kamada, J. Y. Kao, S. Bishu
The paper shows IL-15 promotes inflammatory Th17 cells in the intestine by upregulating RORC via JAK1 in TRM, suggesting IL-15 as a potential therapeutic target for UC.
bioRxiv · Mar 11, 2023 · PreprintImmunology
K. Sugihara, S. Kitamoto, P. Saraithong, H. Nagao-Kitamoto, C. McCarthy, M. Hoostal, A. Rosevelt, C. K. Muraleedharan, M. G. Gillilland, J. Imai, M. Omi, S. Bishu, J. Y. Kao, C. Alteri, N. Barnich, , N. Kamada
The paper shows that mucolytic bacteria enable pathobionts to acquire host-derived nutrients during dietary restriction, allowing them to thrive in the gut.
bioRxiv · Jan 17, 2022Microbiology
Y. Guo, S. Kitamoto, G. Caballero-Flores, D. Watanabe, K. Sugihara, G. Nunez, C. J. Alteri, N. Inohara, N. Kamada
This study identifies adaptation mechanisms of Klebsiella aerogenes in oral and gut mucosae, revealing distinct gene usage for colonization in each environment.
bioRxiv · Jan 13, 2022 · PreprintMicrobiology
H. Hong, N. Mbah, M. Shan, K. Loesel, L. Lin, P. Sajjakulnukit, A. Andren, A. Hayashi, B. Magnuson, Z. Li, Y. Xie, L. Zhang, Y. L. Lei, A. Opipari, R. J. Arguello, , C. A. Lyssiotis
This study shows that OXPHOS enhances TH17 cell survival and persistence by promoting mitochondrial fitness and anti-apoptotic markers.
bioRxiv · Oct 1, 2021 · PreprintImmunology
J. L. Platt, M. G. de Mattos Barbosa, D. Huynh, A. R. Leferts, J. Katta, C. Kharas, P. Freddolino, C. M. Bassis, C. E. Wobus, R. Geha, R. J. Bram, G. Nunez, N. Kamada, M. Cascalho
The paper investigates how a dominant-negative variant of TNFRSF13B confers resistance to enteric pathogens by reducing natural IgA, suggesting balancing selection due to its dual role in immunity and pathogenesis.
bioRxiv · Jan 29, 2021 · PreprintImmunology