Author

J. L. Karlsen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 2 Biophysics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:cryo-EM· 3 Research Focus:protein structure prediction· 3 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Organism:E. coli· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

P. Nissen· 2 shared T. Boesen· 2 shared B. Hove-Jensen· 1 shared B. P. Pedersen· 1 shared C. M. T. Neumann· 1 shared D. E. Brodersen· 1 shared H. H. Gad· 1 shared J. J. Enghild· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiochemistry

P. Nissen

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Structural remodelling of the carbon-phosphorus lyase machinery by a dual ABC ATPase

S. K. Amstrup, N. Sofos, J. L. Karlsen, R. B. Skjerning, T. Boesen, J. J. Enghild, B. Hove-Jensen, D. E. Brodersen

This study reveals how PhnJ mediates ATP hydrolysis-induced structural changes in the C-P lyase complex, uncovering a novel ABC dimer configuration.

bioRxiv · Jun 9, 2022Biochemistry

Cryo-EM structure of the human NKCC1 transporter reveals mechanisms of ion coupling and specificity

C. M. T. Neumann, L. L. Rosenbaek, R. K. Flygaard, M. Habeck, J. L. Karlsen, Y. Wang, K. Lindorff-Larsen, H. H. Gad, R. Hartmann, J. Lyons, R. A. Fenton, P. Nissen

The paper presents a cryo-EM structure of human NKCC1, revealing ion binding sites and mechanisms of ion coupling and specificity.

bioRxiv · Nov 11, 2021Biochemistry

Namdinator - Automatic Molecular Dynamics flexible fitting of structural models into cryo-EM and crystallography experimental maps

R. T. Kidmose, J. Juhl, P. Nissen, T. Boesen, J. L. Karlsen, B. P. Pedersen

Namdinator automates Molecular Dynamics Flexible Fitting to improve structural models in cryo-EM and crystallography maps, achieving model improvements in 87% of tested cases.

bioRxiv · Dec 23, 2018Biophysics