Cellular Senescence Affects ECM Regulation in COPD Lung Tissue
R. R. Woldhuis, N. J. Bekker, J. L. L. Nijnatten, M. Banchero, W. Kooistra, K. J. C. Wolters, P. L. Horvatovich, V. Guryev, M. van den Berge, W. Timens, C.-A. Brandsma
This study identifies ECM gene and protein changes in COPD lung tissue linked to cellular senescence, confirming in vivo associations previously observed in vitro.
bioRxiv · Aug 2, 2023 · PreprintPathology