Author

W. Kooistra

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Assay:proteomics· 1

Frequent Co-Authors

C.-A. Brandsma· 2 shared M. van den Berge· 2 shared R. R. Woldhuis· 2 shared W. Timens· 2 shared J. L. L. Nijnatten· 1 shared K. J. C. Wolters· 1 shared M. Banchero· 1 shared N. J. Bekker· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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2 shared papersCell Biology

C.-A. Brandsma

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Author profile →

2 papers

Recent·Most cited

Strong paracrine effects of SASP from senescence-induced severe early-onset COPD-derived fibroblasts

R. A. Meuleman, W. Timens, W. Kooistra, M. van den Berge, C.-A. Brandsma, R. R. Woldhuis

This study shows that SASP from senescent fibroblasts in severe early-onset COPD promotes paracrine senescence, inflammation, and ECM dysregulation in surrounding fibroblasts.

bioRxiv · Sep 1, 2023 · PreprintCell Biology

Cellular Senescence Affects ECM Regulation in COPD Lung Tissue

R. R. Woldhuis, N. J. Bekker, J. L. L. Nijnatten, M. Banchero, W. Kooistra, K. J. C. Wolters, P. L. Horvatovich, V. Guryev, M. van den Berge, W. Timens, C.-A. Brandsma

This study identifies ECM gene and protein changes in COPD lung tissue linked to cellular senescence, confirming in vivo associations previously observed in vitro.

bioRxiv · Aug 2, 2023 · PreprintPathology