Cancer BiologybioRxiv
Increasing molar activity by HPLC purification improves 68Ga-DOTA-NAPamide tumor accumulation in a B16/F1 melanoma xenograft model
J. L. von Hacht, S. Erdmann, L. Niederstadt…·C. Groetzinger
This study shows that HPLC purification of 68Ga-DOTA-NAPamide increases tumor uptake in B16/F1 melanoma xenografts by removing unlabeled peptide, enhancing molar activity and specific binding.
DOI 10.1371/journal.pone.0217883