Author

J. Liekkinen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Approach:simulation· 1 Approach:statistical model· 1

Frequent Co-Authors

I. Vattulainen· 2 shared J. Bernardino de la Serna· 2 shared M. Javanainen· 2 shared A. Martin· 1 shared A. Olzynska· 1 shared B. de Santos Moreno· 1 shared C. Rossios· 1 shared C. Tempra· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersPharmacology & Toxicology

I. Vattulainen

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2 papers

Recent·Most cited

Exposure to aldehyde cherry e-liquid flavouring and its vape by-product disrupts pulmonary surfactant biophysical function

A. Martin, C. Tempra, Y. T. Yu, J. Liekkinen, R. Thakker, H. Lee, B. de Santos Moreno, I. Vattulainen, C. Rossios, M. Javanainen, J. Bernardino de la Serna

This study shows that benzaldehyde and its by-product, benzaldehyde propylene glycol acetal, disrupt pulmonary surfactant biophysical function by interacting with surfactant proteins SP-B and SP-C.

bioRxiv · Sep 22, 2023 · PreprintPharmacology & Toxicology

Surfactant Proteins SP-B and SP-C in Pulmonary Surfactant Monolayers: Physical Properties Controlled by Specific Protein-Lipid Interactions

J. Liekkinen, A. Olzynska, L. Cwiklik, J. Bernardino de la Serna, I. Vattulainen, M. Javanainen

This study uses molecular dynamics simulations and experimental techniques to investigate how surfactant proteins SP-B and SP-C interact with lipid monolayers, revealing their role in modulating surface pressure and phase behavior.

bioRxiv · Dec 12, 2022 · PreprintBiophysics