Cell BiologybioRxiv
Deconvoluting Stress-Responsive Proteostasis Signaling Pathways for Pharmacologic Activation using Targeted RNA-sequencing
J. M. D. Grandjean, L. Plate, R. I. Morimoto…·R. L. Wiseman
The paper develops a targeted RNA-seq assay to screen and deconvolute stress-responsive signaling pathway activation, demonstrating its utility for identifying selective pharmacologic activators.
DOI 10.1021/acschembio.9b00134