VAV2-DEPENDENT REGULATION OF RIBOSOME BIOGENESIS IN KERATINOCYTES AND ORAL SQUAMOUS CELL CARCINOMA
N. Fernandez-Parejo, L. F. Lorenzo-Martin, J. M. Garcia-Pedrero, J. P. Rodrigo, M. Dosil, X. R. Bustelo
This study shows VAV2 regulates ribosome biogenesis in keratinocytes and oral squamous cell carcinoma, linking it to poor prognosis and identifying RNA polymerase I as a therapeutic target.
bioRxiv · Nov 3, 2023 · PreprintCancer Biology