L. F. Lorenzo-Martin

This study shows VAV2 regulates ribosome biogenesis in keratinocytes and oral squamous cell carcinoma, linking it to poor prognosis and identifying RNA polymerase I as a therapeutic target.

This study reconstructs the colorectal cancer tumor microenvironment using patient-derived organoids and co-cultures, revealing how stromal cells influence cancer behavior and immune evasion.

This paper shows that Vav2 promotes age-dependent transcriptome rewiring in skin stem cells, inducing multiple gene expression waves and altering functional states.

This study shows that lysine acetylation modulates Vav1's adaptor function in lymphocytes by preferentially buffering its ability to stimulate NFAT, distinct from Vav family paralogs.