Author

X. R. Bustelo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Organism:mouse· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

L. F. Lorenzo-Martin· 3 shared J. M. Garcia-Pedrero· 1 shared J. P. Rodrigo· 1 shared L. F. Nevado· 1 shared M. Dosil· 1 shared N. Fernandez-Parejo· 1 shared S. Rodriguez-Fdez· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 13 mutual co-author links

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3 shared papersCancer Biology

L. F. Lorenzo-Martin

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3 papers

Recent·Most cited

VAV2-DEPENDENT REGULATION OF RIBOSOME BIOGENESIS IN KERATINOCYTES AND ORAL SQUAMOUS CELL CARCINOMA

N. Fernandez-Parejo, L. F. Lorenzo-Martin, J. M. Garcia-Pedrero, J. P. Rodrigo, M. Dosil, X. R. Bustelo

This study shows VAV2 regulates ribosome biogenesis in keratinocytes and oral squamous cell carcinoma, linking it to poor prognosis and identifying RNA polymerase I as a therapeutic target.

bioRxiv · Nov 3, 2023 · PreprintCancer Biology

The Rho GTPase exchange factor Vav2 promotes extensive age-dependent rewiring of the skin stem cell transcriptome

L. F. Lorenzo-Martin, X. R. Bustelo

This paper shows that Vav2 promotes age-dependent transcriptome rewiring in skin stem cells, inducing multiple gene expression waves and altering functional states.

bioRxiv · Sep 27, 2022 · PreprintCell Biology

Lysine Acetylation Reshapes The Downstream Signaling Landscape Of Vav1 In Lymphocytes

S. Rodriguez-Fdez, L. F. Nevado, L. F. Lorenzo-Martin, X. R. Bustelo

This study shows that lysine acetylation modulates Vav1's adaptor function in lymphocytes by preferentially buffering its ability to stimulate NFAT, distinct from Vav family paralogs.

bioRxiv · Jan 7, 2020Biochemistry