Author

J. M. McCaw

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 3 Approach:statistical model· 3 Organism:mouse· 2 Approach:Bayesian inference· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1

Frequent Co-Authors

K. Li· 3 shared P. Cao· 3 shared A. C. Hurt· 1 shared A. E. Zarebski· 1 shared J. D. Bloom· 1 shared P. C. Reading· 1 shared R. Farrukee· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 11 mutual co-author links

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3 shared papersImmunology

K. Li

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Enhanced viral infectivity and reduced interferon production are associated with high pathogenicity for influenza viruses

K. Li, J. M. McCaw, P. Cao

This study develops a mathematical model to analyze viral dynamics in HP and LP influenza infections, finding HP viruses have higher infection rates and lower interferon production, leading to more severe tissue damage.

bioRxiv · Jul 29, 2022Immunology

Modelling The Effect of MUC1 on Influenza Virus Infection Kinetics and Macrophage Dynamics

K. Li, P. Cao, J. M. McCaw

This study models how MUC1 affects influenza virus infection and macrophage dynamics, finding it reduces viral reproduction and macrophage recruitment but not viral load.

bioRxiv · Mar 25, 2021Immunology

Modelling within-host macrophage dynamics in influenza virus infection

K. Li, J. M. McCaw, P. Cao

This study develops a mathematical model to explore the relationship between macrophage activation and viral shedding in influenza infection, revealing that macrophage depletion drives the negative correlation between activation and viral shedding.

bioRxiv · May 7, 2020Immunology

Characterization of influenza B virus variants with reduced neuraminidase inhibitor susceptibility

R. Farrukee, A. E. Zarebski, J. M. McCaw, J. D. Bloom, P. C. Reading, A. C. Hurt

This study characterizes two influenza B virus variants with NAI resistance, finding H273Y reduces fitness more than D197N in vivo, while D197N remains prevalent in surveillance.

bioRxiv · Sep 4, 2018Microbiology