Author

P. C. Reading

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 4 Organism:human· 2 Assay:proteomics· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Organism:mouse· 1

Frequent Co-Authors

A. C. Hurt· 2 shared R. Farrukee· 2 shared A. Buness· 1 shared A. E. Zarebski· 1 shared A. J. Corbett· 1 shared B. S. Meehan· 1 shared B. van Wilgenburg· 1 shared C. D'Souza· 1 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersMicrobiology

A. C. Hurt

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

RIG-I activation primes and trains innate antiviral immune memory

M. S. Adamson, S. Nesic, A. Buness, K. Bayrak, S. Schmitz, S. Soler, T. Zillinger, S. Marx, S. Lambing, K. Andryka-Cegielski, F. Khan, T. M. Schlee-Guimaraes, S. Herberhold, M. Proietti, K. Placek, , E. Bartok

RIG-I activation primes and trains innate immune responses, enhancing non-specific antiviral protection in immune and non-immune cells.

bioRxiv · Oct 27, 2022 · PreprintImmunology

Predicting potentially permissive substitutions that improve the fitness of A(H1N1)pdm09 viruses bearing the H275Y NA substitution

R. Farrukee, V. Gunalan, S. Maurer-Stroh, P. C. Reading, A. C. Hurt

This study predicts and validates permissive mutations that could restore fitness to oseltamivir-resistant A(H1N1)pdm09 viruses with the H275Y NA substitution.

bioRxiv · Mar 21, 2021 · PreprintMicrobiology

Characterization of influenza B virus variants with reduced neuraminidase inhibitor susceptibility

R. Farrukee, A. E. Zarebski, J. M. McCaw, J. D. Bloom, P. C. Reading, A. C. Hurt

This study characterizes two influenza B virus variants with NAI resistance, finding H273Y reduces fitness more than D197N in vivo, while D197N remains prevalent in surveillance.

bioRxiv · Sep 4, 2018Microbiology

MAIT cells contribute to protection against lethal influenza infection in vivo

B. van Wilgenburg, L. Loh, Z. Chen, T. J. Pediongco, H. Wang, M. Shi, Z. Zhao, M. Koutsakos, S. Nussing, S. Sant, Z. Wang, C. D'Souza, C. F. Almeida, L. Kostenko, S. B. Eckle, , T. Hinks

This study shows MAIT cells protect against lethal influenza infection by accumulating and being activated early, with their absence increasing mortality in mice.

bioRxiv · Mar 23, 2018Immunology