Author

J. M. Newell

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Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

B. G. Bitler· 1 shared E. S. Dahl· 1 shared K. E. Leon· 1 shared K. M. Aird· 1 shared N. W. Snyder· 1 shared R. Buj· 1 shared

Activity by Year

2018-2018 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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1 shared paperCancer Biology

B. G. Bitler

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1 paper

Recent·Most cited

Targeting IDH1 as a pro-senescent therapy in high-grade serous ovarian cancer

E. S. Dahl, R. Buj, K. E. Leon, J. M. Newell, B. G. Bitler, N. W. Snyder, K. M. Aird

This study identifies IDH1 as a therapeutic target in HGSC by showing its role in promoting metabolic adaptation and epigenetic repression, leading to senescence when inhibited.

bioRxiv · Nov 17, 2018Cancer Biology