Author

J. M. Schwenk

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 5

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Assay:proteomics· 5 Research Focus:cell type annotation· 3 Organism:human· 3 Research Focus:protein folding & dynamics· 2 Research Focus:benchmarking· 1 Approach:statistical model· 1

Frequent Co-Authors

C. Fredolini· 3 shared M. Uhlen· 3 shared T. Dodig-Crnkovic· 3 shared E. Ceraudo· 2 shared E. Lorenzen· 2 shared F. Edfors· 2 shared H. Tegel· 2 shared I. B. Kotliar· 2 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersBiochemistry

C. Fredolini

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Author profile →

5 papers

Recent·Most cited

Itch receptor MRGPRX4 interacts with the receptor activity-modifying proteins (RAMPs)

I. B. Kotliar, E. Ceraudo, K. Kemelmakher-Liben, D. A. Oren, E. Lorenzen, T. Dodig-Crnkovic, M. Horioka-Duplix, T. Huber, J. M. Schwenk, T. P. Sakmar

This study identifies that MRGPRX4 interacts with RAMP2, reducing its signaling and surface expression, and predicts the structure of the MRGPRX4-RAMP2 complex.

bioRxiv · Dec 6, 2022Biochemistry

Multiplexed Analysis of the Secretin-like GPCR-RAMP Interactome

E. Lorenzen, T. Dodig-Crnkovic, I. B. Kotliar, E. Pin, E. Ceraudo, R. D. Vaughan, M. Uhlen, T. Huber, J. M. Schwenk, T. P. Sakmar

This study identifies GPCR-RAMP interactions using a suspension bead array assay, revealing widespread interactions among secretin-like GPCRs and RAMPs.

bioRxiv · Apr 6, 2019Biochemistry

Systematic Development Of Sandwich Immunoassays For The Plasma Secretome

R. S. Haeussler, A. Bendes, M. Iglesias, L. Sanchez-Rivera, T. Dodig-Crnkovic, S. Bystrom, C. Fredolini, E. Birgersson, M. Dale, F. Edfors, L. Fagerberg, J. Rockberg, H. Tegel, M. Uhlen, U. Qundos, J. M. Schwenk

The paper develops a workflow to build dual binder sandwich immunoassays for plasma secretome proteins, validating 102 targets and comparing assay performance with other methods.

bioRxiv · Jan 8, 2019Biochemistry

Screening a Resource of Recombinant Protein Fragments for Targeted Proteomics

F. Edfors, B. Forsstrom, H. Vunk, D. Kotol, C. Fredolini, G. Maddalo, A.-S. Svensson, T. Bostrom, H. Tegel, P. Nilsson, J. M. Schwenk, M. Uhlen

The paper screens a resource of recombinant protein fragments to identify proteotypic peptides for targeted proteomics and demonstrates their utility in quantifying proteins in human plasma.

bioRxiv · Nov 19, 2018Biochemistry

Utilizing a resource of enrichment profiles in plasma for the systematic assessment of antibody selectivity.

C. Fredolini, S. Bystrom, L. Sanchez-Rivera, M. Ioannou, D. Tamburro, R. M. Branca, P. Nilsson, J. Lehtio, J. M. Schwenk

The paper develops a resource of plasma enrichment profiles to assess antibody selectivity by analyzing 414 immunoprecipitation experiments with mass spectrometry.

bioRxiv · Feb 23, 2018Biochemistry