Author

T. Dodig-Crnkovic

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 5

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Assay:proteomics· 5 Research Focus:cell type annotation· 4 Organism:human· 3 Research Focus:benchmarking· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

M. Uhlen· 4 shared A. Bendes· 3 shared J. M. Schwenk· 3 shared T. P. Sakmar· 3 shared E. Ceraudo· 2 shared E. Lorenzen· 2 shared F. Edfors· 2 shared I. B. Kotliar· 2 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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4 shared papersBiochemistry

M. Uhlen

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Author profile →

5 papers

Recent·Most cited

Itch receptor MRGPRX4 interacts with the receptor activity-modifying proteins (RAMPs)

I. B. Kotliar, E. Ceraudo, K. Kemelmakher-Liben, D. A. Oren, E. Lorenzen, T. Dodig-Crnkovic, M. Horioka-Duplix, T. Huber, J. M. Schwenk, T. P. Sakmar

This study identifies that MRGPRX4 interacts with RAMP2, reducing its signaling and surface expression, and predicts the structure of the MRGPRX4-RAMP2 complex.

bioRxiv · Dec 6, 2022Biochemistry

Multiplexed selectivity screening of anti-GPCR antibodies

L. Dahl, I. Kotliar, A. Bendes, T. Dodig-Crnkovic, S. Fromm, A. Elofsson, M. Uhlen, T. P. Sakmar, J. Schwenk

The paper screens 400 anti-GPCR antibodies for selectivity using a multiplexed immunoassay against 215 solubilized GPCRs, finding 61% are selective, 11% bind off-target, and 28% bind none.

bioRxiv · Nov 24, 2022Biochemistry

Facets of individual-specific health signatures determined from longitudinal plasma proteome profiling

T. Dodig-Crnkovic, M.-G. Hong, C. Engel Thomas, R. S. Häussler, A. Bendes, M. Dale, F. Edfors, B. Forsström, P. K. Magnusson, I. Schuppe-Koistinen, J. Odeberg, L. Fagerberg, A. Gummesson, G. Bergström, M. Uhlen, J. Schwenk

This study profiles longitudinal plasma proteomes from healthy individuals to identify individual-specific health signatures and their genetic associations.

bioRxiv · Mar 13, 2020Biochemistry

Multiplexed Analysis of the Secretin-like GPCR-RAMP Interactome

E. Lorenzen, T. Dodig-Crnkovic, I. B. Kotliar, E. Pin, E. Ceraudo, R. D. Vaughan, M. Uhlen, T. Huber, J. M. Schwenk, T. P. Sakmar

This study identifies GPCR-RAMP interactions using a suspension bead array assay, revealing widespread interactions among secretin-like GPCRs and RAMPs.

bioRxiv · Apr 6, 2019Biochemistry

Systematic Development Of Sandwich Immunoassays For The Plasma Secretome

R. S. Haeussler, A. Bendes, M. Iglesias, L. Sanchez-Rivera, T. Dodig-Crnkovic, S. Bystrom, C. Fredolini, E. Birgersson, M. Dale, F. Edfors, L. Fagerberg, J. Rockberg, H. Tegel, M. Uhlen, U. Qundos, J. M. Schwenk

The paper develops a workflow to build dual binder sandwich immunoassays for plasma secretome proteins, validating 102 targets and comparing assay performance with other methods.

bioRxiv · Jan 8, 2019Biochemistry