Metabolic flexibility via mitochondrial BCAA carrier SLC25A44 is required for optimal fever
S. Kajimura, T. Yoneshiro, N. Kataoka, J. M. Walejko, K. Ikeda, Z. Brown, M. Yoneshiro, S. B. Crown, P. White, R. McGarrah, K. Nakamura
This study identifies SLC25A44 as a mitochondrial BCAA carrier essential for metabolic flexibility and optimal fever response through enhanced mitochondrial BCAA oxidation and thermogenesis.
bioRxiv · Jan 29, 2021Cell Biology