Integration in or Near Oncogenes Plays Only a Minor Role in Determining the in Vivo Distribution of HIV Integration Sites Before or During Suppressive Antiretroviral Therapy
J. M. Coffin, M. Bale, D. Wells, S. Guo, B. Luke, J. M. Zerbato, M. D. Sobolewski, T. Sia, W. Shao, X. Wu, F. Maldarelli, M. F. Kearney, J. W. Mellors, S. H. Hughes
The paper compares HIV integration site distributions in vivo and in vitro to assess the role of oncogene integration in viral persistence during ART.
bioRxiv · Nov 25, 2020Microbiology