Author

J. M. Coffin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4

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Research Focus:cell type annotation· 4 Research Focus:gene regulatory network inference· 4 Organism:human· 4 Research Focus:differential expression· 3 Approach:statistical model· 3 Research Focus:clustering· 2 Assay:DNA methylation· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

D. Wells· 2 shared J. W. Mellors· 2 shared M. F. Kearney· 2 shared S. H. Hughes· 2 shared W. Shao· 2 shared X. Wu· 2 shared A. Burn· 1 shared A. Wiegand· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersMicrobiology

D. Wells

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4 papers

Recent·Most cited

The HERV-K(HML-2) Transcriptome in Non-diseased Tissue

A. Burn, F. Roy, M. Freeman, J. M. Coffin

The paper characterizes HERV-K(HML-2) transcriptome expression in non-diseased tissues using GTEx RNA-seq data, finding widespread expression and subgroup-specific tissue biases.

bioRxiv · Jun 24, 2022 · PreprintMicrobiology

Recombinant Origin and Interspecies Transmission of a HERV-K(HML-2)-related Primate Retrovirus 1 With a Novel RNA Transport Element

Z. H. Williams, L. Gaucherand, D. C. Lee, S. M. Mostafa, J. Phelan, J. M. Coffin, W. E. Johnson

The paper identifies recent HML-2 provirus activity in rhesus macaques and shows interspecies transmission to gibbons, with a novel RNA transport element replacing the ancestral Rec-RcRE system.

bioRxiv · May 11, 2022Microbiology

Integration in or Near Oncogenes Plays Only a Minor Role in Determining the in Vivo Distribution of HIV Integration Sites Before or During Suppressive Antiretroviral Therapy

J. M. Coffin, M. Bale, D. Wells, S. Guo, B. Luke, J. M. Zerbato, M. D. Sobolewski, T. Sia, W. Shao, X. Wu, F. Maldarelli, M. F. Kearney, J. W. Mellors, S. H. Hughes

The paper compares HIV integration site distributions in vivo and in vitro to assess the role of oncogene integration in viral persistence during ART.

bioRxiv · Nov 25, 2020Microbiology

Early Emergence and Long-Term Persistence of HIV-Infected T Cell Clones in Children

M. J. Bale, M. G. Katusiime, D. Wells, X. Wu, J. Spindler, E. K. Halvas, J. C. Cyktor, A. Wiegand, W. Shao, M. F. Cotton, S. H. Hughes, J. W. Mellors, J. M. Coffin, G. U. Van Zyl, M. F. Kearney

This study identifies early emergence and long-term persistence of HIV-infected T cell clones in children on antiretroviral therapy, with proviral integration in proto-oncogenes.

bioRxiv · Sep 15, 2020Microbiology